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Updated: Jan 10, 2026

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
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通过依赖于YBX1的m5C修饰对RNF115的上调促进肝细胞癌的进展

Jianhao Li1,2, Han Chen1,2, Lang Bai3,4

  • 1Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, China.

NPJ precision oncology
|November 22, 2025
PubMed
概括

YBX1蛋白驱动肝细胞癌 (HCC) 的进展,通过通过5-甲基细胞素 (m5C) 修改稳定RNF115mRNA,激活PI3K/AKT通路. 这个YBX1/m5C-RNF115轴是HCC的潜在诊断和治疗目标.

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