评估在撒哈拉以南非洲地区对高血压管理的药物服药性研究的实施结果:系统性审查
Chioma Ogechi Egekeze1,2, Chinenye Chukwu3, Dorice Vieira3,4,5
1Teachers College, Columbia University, New York, NY, United States of America. coe2105@tc.columbia.edu.
BMC public health
|November 22, 2025
概括
基于证据的干预措施显著改善了撒哈拉以南非洲的高血压药物坚持. 进一步的研究和利益相关者的意见对于这些战略的实际实施至关重要.
科学领域:
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
- 实施科学 实施科学
背景情况:
- 撒哈拉以南非洲的高血压患病率很高 (高达48%),药物服药率低 (34.1%).
- 有效的高血压管理取决于改善药物坚持.
- 本次审查重点关注该地区对药物坚持的基于证据的干预措施.
研究的目的:
- 系统地审查以证据为基础的干预措施,以改善高血压管理中的药物坚持.
- 评估这些干预措施在撒哈拉以南非洲的实施成果.
- 确定影响高血压管理策略有效实施的因素.
主要方法:
- 来自多个数据库的研究 (RCT,非RCT,混合方法) 的系统审查 (开始-2023年10月).
- 纳入标准:在撒哈拉以南非洲进行的研究,涉及高血压管理和药物坚持,报告实施结果.
- 评估实施结果 (可接受性,采用性,适当性,成本,可行性,忠实性,透性,可扩展性,可持续性) 和偏见风险.
主要成果:
- 14篇文章符合纳入标准,在尼日利亚,乌干达,加纳和南非实施.
- 干预类型包括药剂师主导,护士主导,移动,小组和健康教育方法.
- 所有干预措施都显示了药物坚持度的改善,从1.3%到88%不等. 超过一半的研究报告了适当性,可行性,可接受性和成本.
结论:
- 基于证据的高血压干预措施在改善撒哈拉以南非洲的药物坚持方面是有效的.
- 实施结果为有效的实践者应用提供了洞察力.
- 需要利益相关者的意见和进一步的研究来评估广泛实施的可行性.
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