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Updated: Jan 10, 2026

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在SLE CD4+T细胞中,SETD3通过操纵基因素甲基化和乙化来调节Bcl-6表达和Tfh分化

Shu Ding1, Shengjie Xue2, Yu Rao1

  • 1Department of Dermatology, The Third Xiangya Hospital of Central South University, #138 Tong Zipo Road, Changsha, 410013, Hunan, China.

Clinical epigenetics
|November 22, 2025
PubMed
概括

系统性红斑狼 (SLE) CD4+ T细胞显示SETD3的升高,该细胞通过修改其促进体来调节Bcl-6的表达. 在SLE患者中抑制SETD3可降低Bcl-6表达和Tfh细胞分化.

关键词:
Bcl-6 Bcl-6 Bcl-6 是一个基因组胺基因的修改这就是SETD3D3的意义.一个小小的东西.在 Tfhfh Tfh

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