伊朗男性健康生活方式得分和不孕不育之间的关系:基于人口的病例控制研究
Maryam Rahimi1,2, Peyman Salehi3, Roxana Nematbakhsh1,2
1Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, PO Box 81746-73482, Isfahan, Iran.
Reproductive biology and endocrinology : RB&E
|November 22, 2025
概括
健康的生活方式得分显著降低男性不孕不育的几率,特别是在正常体重的男性中. 采用健康的生活方式模式是管理男性不孕症的关键策略.
科学领域:
- 生殖健康 生殖健康
- 男人的健康 男人的健康
- 生活方式 医学 医疗
背景情况:
- 男性不孕症管理至关重要,个人生活方式因素已知会影响生殖健康.
- 以健康生活方式得分 (HLS) 衡量的生活方式因素对男性不孕不育的综合影响以前未被探索.
研究的目的:
- 评估健康生活方式得分 (HLS) 与伊朗男性不孕症之间的关联.
- 研究生活方式因素在男性不孕症中的作用.
主要方法:
- 一项基于人口的病例控制研究,涉及300名不育男性和300名肥沃对照.
- 通过使用验证的问卷来评估饮食,体育活动,睡眠,吸烟和心理健康,制定了健康生活方式评分 (HLS).
- 根据世界卫生组织 (WHO) 2021年标准诊断出男性不孕症.
主要成果:
- 在完全调整后,拥有最高HLS的男性不孕率明显降低 (OR=0.55;95%CI:0.34-0.90).
- 低心理压力是唯一与降低不孕率有显著关联的个体因素 (OR=0.49;95% CI:0.34-0.71).
- 高HLS与较低不孕率之间的关联在正常体重的男性中最为明显,在超重或肥胖男性中没有发现显著的关联.
结论:
- 综合健康生活方式得分,而不是个人因素,与伊朗男性不孕率较低有关.
- 坚持健康的生活方式模式,尤其是在正常体重的个体中,可以作为男性不孕症管理的有效策略.
- 这项研究强调了对男性生殖健康生活方式的整体方法的重要性.
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