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Updated: Jan 6, 2026

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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Published on: March 18, 2017

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结构控制RNA脱甲基化:G-四重复近距离抑制ALKBH5活动

Keito Obata1, Kamui Tanaka1, Shiroh Futaki1,2

  • 1Institute for Chemical Research, Kyoto University, Kyoto, Japan.

Chemistry (Weinheim an der Bergstrasse, Germany)
|November 22, 2025
PubMed
概括

G-四重复结构比FTO更能抑制ALKBH5的N6-甲基氨酸 (m6A) 脱甲基化,特别是在G四重复核心附近. 这揭示了RNA结构在调节m6A擦拭器中的作用.

关键词:
在G-四重复中.N6 - - 甲基亚诺辛的使用.基因组RNA的修饰是RNA的修饰.在RNA结构中,RNA结构是RNA结构.脱甲基化脱甲基化

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