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Updated: Jan 6, 2026

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions

Published on: January 20, 2022

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甘氨酸RNAdb:一个数据库的甘氨酸RNA序列,结构,丰富度,并在组织和细胞系的甘氨酸信息

Chuxin Zheng1, Ying Ao2, Zhen Zhang1

  • 1MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, Innovation Center for Evolutionary Synthetic Biology, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Agriculture and Biotechnology, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.

Nucleic acids research
|November 22, 2025
PubMed
概括

糖化RNAs (glycoRNAs) 是新发现的细胞表面分子,对细胞通信至关重要. GlycoRNAdb是第一个集中了glycoRNA数据的数据库,有助于研究它们的功能和治疗用途.

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Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
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Proteoglycans01:05

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Protein Glycosylation01:25

Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
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