儿童和青少年接触敏感:多中心欧洲研究 (2011-2022) 的趋势 (2011-2022)
Roberto Mazzetto1,2, Wolfgang Uter3, Aleksandra Dugonik4
1Dermatology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
概括
接触过敏在儿童中很常见,具有不断变化的敏感化模式. 年龄较小的儿童表现出更高的和烯酸盐过敏,而青少年则增加了对二 (PPD) 的敏感性.
科学领域:
- 儿科皮肤病学 儿科皮肤病学
- 过敏学 过敏学
- 公共卫生 公共卫生
背景情况:
- 接触过敏是儿童的重大健康问题,但欧洲的全面数据是有限的.
- 本研究分析了2011-2022年欧洲接触过敏监测系统 (ESSCA) 的数据,提供了更新和广泛的儿科贴片测试数据集.
研究的目的:
- 分析欧洲儿科接触敏感化的当前趋势.
- 为了比较不同年龄组和地理区域之间的敏感化模式.
- 确定关键的过敏原及其在儿童和青少年中的流行率.
主要方法:
- 对11个欧洲国家的6961名儿童和青少年 (1至16岁) 的标准化贴片测试数据的回顾性分析.
- 敏感化率的评估,年龄特定的过敏原模式,以及与亚托皮炎的关联.
- 与之前的ESSCA研究数据 (2002-2010) 的比较.
主要成果:
- 总体接触敏感率为29.3%,在最年轻的儿童 (1-5岁) 中患病率更高,为34.3%.
- 年龄较小的儿童 (1-5岁) 与青少年 (13-16岁) 相比,对硫酸,甲基异索 (MI) 和化的敏感性更高.
- 青少年 (13-16岁) 与年轻儿童相比,对二 (PPD) 的敏感性增加了三倍;观察到阳性的区域差异.
结论:
- 接触过敏仍然在儿童群体中普遍存在,受法规和社会因素影响的敏感性概况不断变化.
- 显著的与年龄相关的过敏原敏感性差异 (,烯酸盐,PPD) 强调需要针对年龄特定的预防策略.
- 持续的区域差异和年幼儿童的高患病率强调了持续监测和更新儿科贴片测试指南的必要性.
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