新兴的非热技术用于生产后生物制剂
Rohit Thirumdas1, Priti Mudgil2
1MFPI-Quality Control Laboratory, Professor Jayashankar Telangana Agricultural University, Hyderabad, India.
Comprehensive reviews in food science and food safety
|November 22, 2025
概括
与传统的杀热技术相比,非热处理为生产后生物制剂提供了优越的方法,提高了稳定性和健康益处. 这些先进的方法对功能性食品和补充剂的工业应用有希望.
科学领域:
- 食品科学与技术 食品科学与技术
- 微生物学 微生物学
- 生物技术是生物技术.
背景情况:
- 后生物质,即无生命的微生物成分,正在成为功能性食品和补充剂的关键成分.
- 对于后生物生产的传统热杀死方法存在一些缺点,例如改变了味道和降低了生物活性.
- 非热技术比后生物生产的热处理具有潜在的优势.
研究的目的:
- 审查和比较新兴的非热技术与传统的后生物生产方法.
- 评估通过非热方法生产的后生物质的工业适用性,生物活性,稳定性和功能价值.
- 确定在后生物制造中扩大非热技术的挑战和机会.
主要方法:
- 非热处理技术的文献综述,包括HPP,PEF,超声波,冷等离子体,Sc-CO2和辐射.
- 分析原则,工业适用性和对后生物质量的影响.
- 评估每个技术的优势,局限性和优化潜力.
主要成果:
- 像HPP和PEF这样的非热技术显示出保存后生物生物活性和功能价值的潜力.
- 与热杀死后生物相比,这些方法提供了更好的稳定性和配方灵活性.
- 对于工业实施,确定了扩展,参数优化和监管合规方面的挑战.
结论:
- 新兴的非热技术为后生物生产提供了重要的创新机会.
- 需要进一步的研究和证据来确认工业整合的可行性,成本效益和安全性.
- 优化无活化,暴露反应和临床影响的协议对于推进非热后生物制造至关重要.
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