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评估预训练的蛋白质语言模型嵌入作为功能相似性的代理

Robert Shaw1, Samuel D Love1, Claire D McWhite2

  • 1Department of Molecular and Cellular Biology, The University of Arizona, Tucson, AZ, USA.

Journal of molecular evolution
|November 22, 2025
PubMed
概括

蛋白质语言模型 (PLMs) 生成数值嵌入,可以表示蛋白质结构和功能. 这些嵌入显示了检测微妙的功能差异和与功能保存相关的潜力.

关键词:
功能上的相似性.蛋白质语言模型的模型

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