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使用针对性MRI信息的微超声波活检检测临床意义上的前列腺癌
Allison B Forrest1, Danielle E Kruse1, Brian Calio2
1Department of Radiology, Duke University Medical Center, Durham, NC, USA.
European radiology
|November 22, 2025
概括
微超声导向活检成功检测出临床显著的前列腺癌 (csPCa),其速率与MRI-超声融合活检相美. 这表明微超声波是cspca检测的可行替代方案.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 多参数MRI (mpMRI) 对于检测临床显著的前列腺癌 (csPCa) 是至关重要的.
- 微超声波 (microUS) 引导的活检为向性前列腺癌检测提供了一种新的方法.
- 需要与已建立的融合活检技术进行直接比较.
研究的目的:
- 为了比较使用mpMRI信息的微US导向活检与历史的mpMRI-超声波 (mpMRI-US) 融合活检的csPCa检测率.
- 评估微US导向活检的积极预测值 (PPV) 以检测csPCa.
主要方法:
- 对接受mpMRI信息微US导向活检的患者的回顾性分析.
- 用PI-RADS和PRI-MUS分数计算PPV的方法.
- 微US引导活检结果与历史的mpMRI-US融合活检数据的比较.
主要成果:
- mpMRI发现了244个病变;84.4%在microUS上可视化,还有26个额外的microUS病变.
- 在41.4%的患者中,microUS导向活检检测到csPCa,另外1.8%来自microUS-only病变.
- 对csPCa的PPV在具有微US相关的病变 (0.37) 和没有 (0.18) 的病变中显著更高.
- 与历史的mpMRI-US融合活检数据 (p > 0.05) 相比,检测率没有显著差异.
结论:
- 微US引导活检成功实施,并实现了与mpMRI-US融合活检相似的csPCa检测率.
- mpMRI和microUS的组合可以提高csPCa的检测.
- 微US导向活检显示性能与mpMRI-US融合活检相当.
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