基于计算机断层扫描的荷兰人口的肌肉和脂肪组成:一个横截面研究
Arthur A R Sweet1,2, Tim Kobes3,4, Roderick M Houwert3
1Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. a.a.r.sweet@outlook.com.
Insights into imaging
|November 22, 2025
概括
这项研究通过CT扫描在荷兰成年人身上确定了身体组成的欧洲参考值. 它揭示了与年龄相关的肌肉质量下降和内脏脂肪增加,这对于个性化健康评估至关重要.
科学领域:
- 放射学和成像学 放射学和成像学
- 人体生理学 人体生理学
- 老年学是指老年学的学科.
背景情况:
- 来自北美的成年人体构成规范性数据存在,但缺乏欧洲特定的,经性别和年龄调整的参考值.
- 肥胖和肉是疾病和死亡的重要风险因素.
- 基于计算机断层扫描 (CT) 的身体组成分析为个性化医学提供了精确的肌肉和脂肪量化.
研究的目的:
- 通过CT成像在欧洲成年人群中确定体质成分参数的性别和年龄特定的参考值.
- 为荷兰成年人提供CT衍生体质成分参考曲线,用于临床应用.
- 为了研究肌肉质量和脂肪分布的年龄和性别相关变化.
主要方法:
- 一项采用成年创伤患者CT扫描 (n=2286) 来自1级创伤中心的横截面研究.
- 一个人工智能算法在第三个腰椎水平上自动细分肌肉和脂肪组成部分.
- 计算了骨肌肉指数,并分析了肌肉衰减和内脏脂肪区域,生成特定于年龄和性别的百分位曲线.
主要成果:
- 在男性中,总肌肉指数随着60岁左右的年龄而下降,而在女性中,当不包括肌内脂肪时则下降.
- 平均肌肉衰减在两性中随着年龄的增长而大幅下降.
- 在两性中,内脏脂肪区域随着年龄的增长而迅速增加,在男性中观察到更高的值.
结论:
- 本研究提出了首个CT-derived欧洲参考值,用于荷兰成年人的身体组成.
- 这些参考值旨在用于临床实践,以帮助个性化风险评估和治疗.
- 基于CT的身体成分评估对于识别个体风险和改进患者护理策略是有价值的.
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