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Updated: Jan 10, 2026

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功能性S-化探索揭示了HNF1α的新型调节机制

Yaqian Huang1, Zongmin Li1, Shuai Wang2

  • 1Department of Pediatrics, Children's Medical Center, Peking University First Hospital, Beijing, 100034, China.

Redox biology
|November 22, 2025
PubMed
概括

硫化 (H2S) 修改蛋白质,但遗漏了像转录因子这样的低丰富度调节剂. 这项研究确定了HNF1α S-过硫化,揭示了影响脂质代谢和心血管健康的氧化还原机制.

关键词:
半氨酸蛋白质组的蛋白质组是什么肝细胞核因子-1αα硫化是一种硫化.这是一种S-超硫化.转录因子是一种转录因子.

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