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使用Ficus hispida乙烯酸提取物合成的生物工程纳米颗粒表现出抗菌和抗氧化活性

Jatla Murali Prakash¹, Palanisamy Pethappachetty², Raslamol Kannurkaran³

¹Department of Chemistry, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, 522302, Andhra Pradesh, India.

Microbial pathogenesis

|November 22, 2025

概括

使用Ficus hispida提取物合成的绿色纳米粒子 (Se-NPs) 显示出有前途的抗氧化和抗菌特性. 这些环保的Se-NP显示出对抗多药耐药细菌的进一步生物医学应用的潜力.

科学领域:

纳米技术纳米技术
材料科学材料科学材料科学
生物医学工程生物医学工程

背景情况:

多种耐药细菌的兴起需要新的抗微生物战略.
通过绿色化学合成的纳米粒子 (Se-NPs) 由于其固有的抗氧化和抗菌特性,提供了一个有前途的途径.

研究的目的:

使用Ficus hispida提取物合成和表征纳米粒子 (Se-NPs).
评估合成的Se-NPs的抗氧化和抗菌生物活性.

主要方法:

使用Ficus hispida水果提取物和甲酸合成了Se-NP.
鉴定包括UV-Vis,FT-IR,XRD,FE-SEM,HR-TEM,泽塔潜力和EDAX分析.
使用DPPH测定抗氧化能力和阿加井扩散测定抗 E. coli,B. subtilis和S. aureus的抗菌功效,评估了生物活性.

主要成果:

鉴定证实了晶体,六角形Se-NP的形成,其大小在7.59-12.26nm (HR-TEM) 之间.
合成的Se-NP表现出显著的抗氧化活性 (71%的抑制在100μg/mL).
抗菌试验显示了针对大肠杆菌 (14毫米),B. subtilis (14毫米) 和金黄色杆菌 (18毫米) 的显着抑制区,观察到金黄色杆菌的形态损伤.

结论:

菲库斯海斯皮达介导的Se-NP是环保的,具有良好的特征,并具有显著的抗氧化和抗菌特性.
这些FH-Se-NP对格朗阳性细菌表现出特别的疗效.
该研究支持FH-Se-NPs作为生物医学应用中的替代治疗剂的潜力.

关键词:

抗菌功效. 抗菌的功效. 抗菌的功效. 绿色合成是一种绿色合成.抗氧化剂活性抗氧化剂活性菲库斯·希斯皮达 (Ficus hispida) 提取物是一种植物提取物.纳米粒子是一种纳米粒子.

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