相关实验视频

Updated: Aug 8, 2026

A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure
09:06

A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure

Published on: October 24, 2018

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一种用于DNA甲基组分析的平滑方法,以增强在全表观基因组关联研究中的表观基因组特征检测

Abderrahim Oussalah1, Loris Mousel2, David-Alexandre Trégouët3

  • 1University of Lorraine, INSERM UMR_S 1256, Nutrition, Genetics, and Environmental Risk Exposure (NGERE), Faculty of Medicine of Nancy, Nancy F-54000, France; Department of Genomic Medicine, Division of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy, Nancy F-54000, France; Reference Center for Inborn Errors of Metabolism (ORPHA67872), French National Network for Inherited Metabolic Disorders (G2M), University Hospital of Nancy, Nancy F-54000, France.

Methods (San Diego, Calif.)
|November 22, 2025
PubMed
概括

我们开发了一种新的平滑方法,通过提高信号与噪声的比率和减少错误阳性来改进表观基因组范围的关联研究 (EWAS),使得在较小的队列中进行发现. 这种方法有效地识别了各种人类特征和疾病中的关键表观遗传学特征.

关键词:
基因组甲基组组的DNA.整个表观基因组的关联研究.表观遗传学签名是指表观遗传学签名.萨维茨基 戈莱 过器信号与噪声的比率.滑方法是一种光滑方法.CpG二核酸的联合甲基化模式

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Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies14:56

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

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