用OSA修饰的米,脱枝,以及封装ferulic acid的可溶性粉:界面效应和增强的溶解性,稳定性,生物活性和持续释放性
Linlin Chen1, Zhang Ming1, Wei Li1
1Key Laboratory of Food Science and Engineering of Heilongjiang Province, College of Food Engineering, Harbin University of Commerce, Harbin, 150028, PR China.
International journal of biological macromolecules
|November 22, 2025
概括
化粉有效封装酸 (FA),增强其稳定性和生物可用性. 酸复合物与八酸酸无水化脱枝粉 (OSA-DBS) 显示出优异的抗氧化和抗菌特性和受控释放.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学 材料科学 材料科学
- 生物化学 生物化学
背景情况:
- 酸 (FA) 具有显著的抗氧化,抗炎和抗癌特性.
- 缺乏稳定性,溶解性和生物利用性限制了FA在食品,制药和化品行业的应用.
研究的目的:
- 通过与改性粉复合,增强酸 (FA) 的稳定性和生物可用性.
- 评估FA-粉复合物的抗氧化活性,稳定性和体外释放.
主要方法:
- 用酸 (FA) 复合物的制备,使用酸化物 (OSA) 改性大米粉 (RS),脱枝粉 (DBS) 和可溶性粉 (SS).
- 评估FA复合物的封装效率,抗氧化活性,稳定性和体外释放动力学.
- 封装机制的分析,包括键,范德瓦尔斯力和疏水相互作用.
主要成果:
- 由于其紧的结构,octenyl succinic anhydride-debranched粉 (OSA-DBS) 显示了最高的封装效率.
- 与其他复合物相比,FA@OSA-DBS表现出增强的抗氧化和抗菌活性,提高溶解度和稳定性.
- 在体外释放研究表明,在模拟生理环境中,FA@OSA-DBS的缓慢,第一阶段释放率.
结论:
- 化粉,特别是OSA-DBS,有效地改善了酸 (FA) 的物理和化学特性.
- 这项研究为开发功能材料的酸粉复合系统提供了理论基础.
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