相关实验视频

Updated: Jan 10, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

快速进步者在中央与全球视野中的比例,跨越不同眼症严重程度组

Gopikasree Gunasegaran¹, Sasan Moghimi¹, Takashi Nishida¹

¹From the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA.

American journal of ophthalmology

|November 22, 2025

概括

中央视野进展在绿眼病患者中比全球进展更为常见. 密切监测中心视力变化对于所有格洛科马严重程度阶段至关重要.

科学领域:

眼科医生眼科眼科
眼镜测量是指眼睛的测量.
视觉科学科学视觉科学

背景情况:

玻璃眼是全球不可逆转的失明的主要原因.
早期检测和视野 (VF) 进展的监测对于治疗青光眼的管理至关重要.
评估VF进展可以在全球范围内进行,也可以专注于特定地区,例如中央10°.

研究的目的:

为了比较快速中心VF进展的患病率与全球VF进展在初级开角绿内障 (POAG) 患者.
分析不同青光眼严重程度阶段 (早期,中度,晚期) 的进展率.

主要方法:

从759名POAG参与者中对1117只眼睛进行了回顾性队列研究.
最少2年的随访时间,至少5次24-2VF测试.
计算的全球平均偏差 (MD) 和中央平均总偏差 (MTD₁₀) 的进展率.
定义的快速进展为MD的≤-1.0dB/年,MTD₁₀的≤-0.5dB/年.

主要成果:

总体而言,12.8%的眼睛表现出快速的中央进展 (MTD₁₀),而全球进展 (MD) 的比例为7.5%.
在10.8% (早期),15.2% (中度) 和20.9% (晚期) 青光眼中检测到快速的中心进展.
很大一部分眼睛 (5.5%15.1%) 呈现出快速的中央进展,没有同时出现快速的全球进展.

结论:

与全球VF分析 (MD) 相比,中央视野 (MTD₁₀) 分析在所有格洛科马严重程度上发现了更高比例的快速进展者.
这些发现强调了监测中心VF变化的重要性,以便在所有青光眼患者中及时干预.

更多相关视频

Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing

Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing

Published on: February 23, 2024

Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping

Author Spotlight: Insights into Visual Cortex Research Through Wide-View fMRI Mapping

Published on: December 8, 2023

相关概念视频

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...