将草本基因组学与系统生物学方法相结合,以实现药用植物资源的可持续利用
Tanvi Gupta1, Jyoti Upadhyay2, Sudesh Kumar Yadav3
1CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, India.
Drug discovery today
|November 22, 2025
概括
草基因组学将奥米克技术与传统知识相结合,以了解药用植物. 这种方法有助于可持续的保护,精密育种和开发新的植物性疗法.
科学领域:
- 植物科学 植物科学
- 基因组学就是基因组学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 全球对草药的依赖需要药用植物的可持续实践.
- 草基因组学将奥米克技术与传统知识相结合,研究植物遗传学和生物活性化合物.
研究的目的:
- 探索草本基因组学在了解药用植物生物学方面的潜力.
- 调查奥米克技术如何有助于医用植物的保护和利用.
主要方法:
- 利用基因组学,转录组学,代谢组学和蛋白质组学来分析植物遗传学和生物合成途径.
- 整合多学科数据与传统知识.
主要成果:
- 在二次代谢物生物合成中揭示了复杂的调节网络.
- 确定了参与生物活性化合物生产的关键途径和酶.
结论:
- 草本基因组学为优化草本资源提供了坚实的基础.
- 多omics方法通过精密育种和代谢工程加速了基于植物的治疗方法的发展.
相关概念视频
Plant Breeding and Biotechnology
21.4K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
21.4K
Transgenic Plants
8.4K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
8.4K
Transgenic Organisms
33.1K
Overview
33.1K
Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
161
Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...
161


