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相关概念视频

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.9K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.9K
Development of Immunocompetence01:22

Development of Immunocompetence

774
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
774
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

2.9K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
2.9K
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

1.3K
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
1.3K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

1.7K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
1.7K
Immunological Memory01:23

Immunological Memory

15.0K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
15.0K

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相关实验视频

Updated: Jan 10, 2026

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
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Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays

Published on: September 20, 2024

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当前的概念:常见的变量免疫缺陷.

Charlotte Cunningham-Rundles1

  • 1David S. Gottesman Professor of Immunology Department of Medicine, Department of Pediatrics, Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
|November 22, 2025
PubMed
概括
此摘要是机器生成的。

常见变性免疫缺陷 (CVID) 是一种常见的原发性免疫障碍,影响成年人,其特点是抗体水平低和反应差. 早期诊断是至关重要的,因为它的各种症状和常见的诊断延迟.

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Development of an IFN-&#947; ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
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Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

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Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR
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Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR

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相关实验视频

Last Updated: Jan 10, 2026

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
06:03

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays

Published on: September 20, 2024

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Development of an IFN-&#947; ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
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Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

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Simultaneous Quantification of T-Cell Receptor Excision Circles TRECs and K-Deleting Recombination Excision Circles KRECs by Real-time PCR
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科学领域:

  • 免疫学 免疫学 免疫学
  • 临床医学 临床医学
  • 遗传学 是一个遗传学.

背景情况:

  • 常见变性免疫缺陷 (CVID) 是最常见的症状性初级免疫缺陷.
  • 它表现为免疫球蛋白水平 (IgG,IgA,IgM) 降低和抗体反应受损.
  • 尽管它是一种原发性免疫缺陷,但诊断通常发生在20-40岁之间,有显著的延迟.

研究的目的:

  • 为提供关于CVID的全面概述.
  • 讨论诊断标准,临床表现和治疗.
  • 突出新兴的遗传洞察力和需要提高医生意识.

主要方法:

  • 对CVID早期病史和诊断标准的审查.
  • 对临床表现和炎症并发症的分析.
  • 检查当前的遗传学理解和治疗方式.

主要成果:

  • 冠状病毒感染 (CVID) 是一个总体术语,涵盖了许多免疫缺陷,许多尚未被发现.
  • 由于异质的临床表现,诊断延迟很常见.
  • 由于CVID的流行率和并发症,对各种医疗专家来说,意识至关重要.

结论:

  • COVID需要在医疗保健提供者中得到更广泛的认可.
  • 进一步的遗传研究对于完善诊断和治疗至关重要.
  • 及时诊断和管理是改善患者治疗结果的关键.