患有初级先天性玻璃眼的儿童的矮身 - - 一个回顾性横截面研究
Rafaa Babgi1, Ibrahim AlObaida1, Adi Mohammed Al Owaifeer2
1King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
概括
患有初级先天性玻璃眼 (PCG) 的儿童可能会出现矮身. 这项试点研究发现PCG和身高下降之间存在显著的关联,尽管体重对于年龄来说通常是正常的.
科学领域:
- 眼科医生 眼科 眼科
- 儿科 儿科 儿科
- 遗传学 是一个遗传学.
背景情况:
- 临床观察表明,初级先天性玻璃眼 (PCG) 与儿童的矮身之间存在联系.
- PCG是一种罕见的遗传疾病,影响婴儿,其特点是眼内压力升高和视神经损伤.
研究的目的:
- 调查小儿患者中初级先天性玻璃眼 (PCG) 和矮身之间的潜在关联.
- 为了确定被诊断为PCG的儿童是否表现出生长模式,表明身材矮小.
主要方法:
- 对2014年1月至2020年12月期间被诊断患有PCG的93名儿童的医疗记录的回顾性审查.
- 提取基线特征,身高和体重数据;使用标准生长图表计算身高和体重Z-score.
主要成果:
- 在93名PCG患者中,近一半的患者 (46%) 表现出中度至严重的矮身 (Z评分<-2).
- 很大一部分人 (29%) 严重身高矮 (Z评分< -3).
- 尽管身高矮小,但只有6%的患者被归类为体重不足,这表明他们的体重与年龄相比是正常的.
结论:
- 这项研究表明,初级先天性玻璃眼与儿童的矮身之间存在潜在的相关性.
- 建议对更大群体进行进一步的前性研究,以证实这些发现,并探索社会经济地位等混因素.
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