产前代谢,胆乳和母牛小牛的发展之间的关联
Yapin Wang1, Aart Lammers1, Joop Arts1
1Adaptation Physiology Group, Wageningen University & Research, 6708 WD Wageningen, the Netherlands.
Journal of dairy science
|November 22, 2025
概括
孕产妇产前饮食和能量平衡通过胆乳成分影响乳牛的免疫力. 较高的水能量平衡和干物质摄入与乳母乳和后代血中自然抗体水平的增加相关,促进长期免疫力.
科学领域:
- 动物科学动物科学
- 生殖生物学 生殖生物学
- 免疫学 免疫学 免疫学
背景情况:
- 乳酪质量对于后代的健康和免疫力至关重要.
- 孕产妇产前状态会影响胆乳的组成和免疫的转移.
- 了解这些关系可以优化小牛的发育和长期健康.
研究的目的:
- 调查母婴产前状态,母乳粉和后代生长/代谢之间的联系.
- 检查胆汁对从出生到哺乳期的后代的影响.
- 将母乳母乳的特征与产后后代的特征进行相关联.
主要方法:
- 分析了62名荷尔斯坦-弗里西亚人母的产前变量 (BW,BCS,DMI,EB) 和血液代谢物.
- 在分娩后测量了胆乳产量,Brix,蛋白质,生长因子和抗体.
- 在三个发育阶段监测后代 (n=62) 的体重和血液代谢物.
主要成果:
- 较高的产前身体状况得分 (BCS) 与较低的乳酸铁素相关.
- 较大的能量平衡 (EB) 与较高的IgM相关,影响后代血IgG和IgM.
- 大奶粉中IGF-I和TGF-β2的增加与后代的非化脂肪酸和牛奶乳糖有关.
- 母乳产量预测后代母乳产量.
结论:
- 乳干物摄入量 (DMI) 和EB积极影响乳酪的天然抗体水平.
- 大奶粉的抗体水平与从出生到哺乳期的后代血抗体水平直接相关.
- 产前母亲的营养和代谢状况显著影响子女的终身免疫力.
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