相关实验视频

Updated: Jan 10, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

在儿童中枢神经系统瘤中的 (23Na) 核磁共振

Aashim Bhatia¹, Em Triolo¹, L Tyler Williams¹

¹Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Neuroimaging clinics of North America

|November 22, 2025

概括

这项研究引入了一种先进的Na-MRI技术,为脑瘤成像提供了卓越的对比度和分辨率. 这种方法在临床上是可行的,有助于在治疗期间探索度.

科学领域:

医疗成像医学成像
神经瘤学神经瘤学
生物标志物开发生物标志物开发

背景情况:

1H-MR成像在评估瘤生物学方面存在局限性.
现有的Na-MRI技术取得了初步成功,但需要改进.
在神经瘤学中需要先进的成像生物标志物.

研究的目的:

为神经瘤学提供一种增强的Na-MRI技术.
与以前的方法相比,证明了较好的对比度和分辨率.
评估新的Na-MRI序列在脑瘤患者的临床可行性.

主要方法:

使用扭曲投影成像采集.
采用了解剖学指导的重建.
在临床前瘤模型和临床环境中验证了该技术.

主要成果:

在Na-MRI中获得了更好的对比度和分辨率.
在脑瘤患者中证明了该序列的临床可行性.
能够进一步探索治疗期间瘤模型中的度.

结论:

改进的Na-MRI技术比以前的方法具有显著的优势.
这种方法适合在神经瘤学中临床使用.
23Na-MRI具有作为改善的成像生物标志物,反映瘤生物学的潜力.

关键词:

大脑瘤大脑瘤儿科大脑的儿童大脑核磁共振成像 (MRI) 的成像

更多相关视频

Measurement Of Neuromagnetic Brain Function In Pre-school Children With Custom Sized MEG

Measurement Of Neuromagnetic Brain Function In Pre-school Children With Custom Sized MEG

Published on: February 19, 2010

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Other Nuclides: 31P, 19F, 15N NMR

Other Nuclides: ³¹P, ¹⁹F, ¹⁵N NMR

Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...