儿科手术患者的输血和结果:一个11年后期的北美队列研究
Susan M Goobie1, David Faraoni1
1Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
British journal of anaesthesia
|November 22, 2025
概括
儿童手术中的红细胞 (RBC) 输血在十年内增加,与更高的死亡率和并发症有关. 对于接受手术的出血和贫血儿童,谨慎管理至关重要.
科学领域:
- 儿科手术 儿科手术
- 输血医学 输血医学
- 改善医疗保健质量 改善医疗保健质量
背景情况:
- 儿科外科手术期间输血的趋势没有得到充分的记录.
- 了解儿童的输血发生率和结果对于改善护理至关重要.
研究的目的:
- 为了确定红细胞 (RBC) 输血在儿科手术患者的发生率.
- 评估红细胞输血与该人群中不良结果之间的关联.
主要方法:
- 使用美国外科医生学院国家外科质量改善计划儿科数据库 (2012-2023) 进行回顾性队列研究.
- 包括1,303,500名接受非心脏手术的儿科患者 (0-18岁).
- 使用统计分析,包括多变量逻辑回归,比较输血和未输血患者之间的结果.
主要成果:
- 6.3%的儿科患者接受了红细胞输血,在11年研究期间 (4.7%至7%) 观察到日益增长的趋势.
- 输血患者的30天死亡率 (2.4%与0.2%) 和并发症率 (调整后P<0.001) 显著增加.
- 新生儿和老年儿童的输血率和不良结果较高,输血与30天死亡率之间存在独立关联 (aOR 2.11).
结论:
- 十年的数据显示,儿科手术中红细胞输血的发生率越来越高,与较差的结果有关.
- 术后输血管理中的警和有针对性的干预措施是必要的,以减轻脆弱的儿科手术患者的风险.
关键词:
保护血液 保护血液死亡率 死亡率儿科麻醉 儿科麻醉患者的血液管理 患者的血液管理在外科手术期间的结果.红细胞是红血细胞的组成部分.手术 手术 手术 手术 手术 手术 手术输血是输血的方法之一.更多相关视频
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