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Updated: Jan 10, 2026

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets
11:19

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets

Published on: July 7, 2010

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整合全基因组和转录基因组测序来表征异形变异的遗传结构

Chunyu Liu1,2, Roby Joehanes3, Jiantao Ma4

  • 1Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA. liuc@bu.edu.

Nature communications
|November 22, 2025
PubMed
概括

这项研究引入了一种全血同型比率QTL (irQTL) 的新型资源,识别了数百万个调节特定基因同型的遗传变异. 这些irQTLs揭示了异形特异性调节,并将遗传变异与血压等复杂特征联系起来.

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Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq06:24

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Published on: March 12, 2021

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Author Spotlight: Multi-Layered Approach to Understand Postnatal Functions of Pancreatic Islets in Non-Human Primates03:39

Author Spotlight: Multi-Layered Approach to Understand Postnatal Functions of Pancreatic Islets in Non-Human Primates

Published on: November 8, 2024

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Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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Genomics02:02

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Genome Annotation and Assembly03:36

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