与外围动脉疾病和高脂血症相关的死亡率的趋势和差异,1999-2024年
Saifullah Khan1, Muhammad Hassan1, Muhammad Hussain1
1Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Scientific reports
|November 22, 2025
概括
美国的外周动脉疾病 (PAD) 和高脂血症的死亡率显著增加,从1999年到2024年增加了五倍以上. 这些趋势显示了日益扩大的差距,特别是影响男性,西班牙裔人口和农村居民.
科学领域:
- 心血管疾病流行病学
- 公共卫生趋势 公共卫生趋势
- 健康差距 研究 研究 研究 研究
背景情况:
- 周围动脉疾病 (PAD) 和高脂血症是导致心血管疾病负担的主要原因.
- 人口水平的死亡率趋势和高脂血症PAD的差异尚不清楚.
- 了解这些趋势对于公共卫生干预和资源分配至关重要.
研究的目的:
- 在美国调查与PAD和高脂血症相关的死亡率的长期时间模式.
- 为了确定PAD和超脂血症相关死亡率的人口和地理差异.
- 为预防和管理心血管疾病制定有针对性的公共卫生战略提供信息.
主要方法:
- 来自CDC WONDER数据库 (1999-2024) 的全国代表性死亡记录的分析.
- 每10万人口的年龄调整死亡率 (AAMR) 的计算,标准化为2000年美国标准人口.
- 关联点回归分析以确定时间趋势 (年平均百分比变化 - AAPC) 并确定重大变化.
主要成果:
- 在25岁以上的美国成年人中,共有148,416人死于PAD与高脂血症.
- 国家AAMR从1999年的0.74增加到2024年的3.92 (AAPC为6.32%).
- 所有人口群体的死亡率都上升,男性,西班牙裔个人,西部地区和农村地区的死亡率更高,增长更快.
结论:
- 在全国范围内,PAD和高脂血症的死亡率增加了五倍以上,这表明公共卫生问题越来越严重.
- 存在显著的差异,男性,西班牙裔人口以及西部地区和农村地区的居民的死亡率不成比例地高且不断增加.
- 迫切需要加强预防措施,改进脂质管理策略和公平获得心血管保健,以解决日益扩大的血管健康差异.
更多相关视频
09:06Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
8.7K
07:25Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
3.7K
相关概念视频
01:30Peripheral Artery Disease I: Introduction
290
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
290
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
330
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
330
01:27Peripheral Artery Disease III: Interprofessional Care
229
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
229
01:26Peripheral Artery Disease IV: Nursing Management
325
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
325
01:30Coronary Artery Disease I: Introduction
857
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
857
01:23Atherosclerosis IV: Nursing Management
351
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
351