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在患有多器官功能障碍综合征的重症重症病重症监护室患者中,早期死亡风险评估的布拉登评分

Weizhu Deng¹, Ximu Zhang², Xiaoli Liu³

¹Department of Nephrology, First Medical Center of Chinese, State Key Laboratory of Kidney Diseases, PLA General Hospital, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, 100853, China.

Scientific reports

|November 22, 2025

概括

布拉登评分与多器官功能障碍综合征 (MODS) 患者的ICU死亡率有负相关性. 较低的布雷登分数表明死亡风险较高,突出显示其在预测重症患者预后方面的重要性.

科学领域:

关键护理医学关键护理医学
临床风险评估临床风险评估
患者的治疗结果.

背景情况:

多器官功能障碍综合征 (MODS) 带来了重大挑战,包括长时间住院和高死亡率.
确定MODS患者的死亡风险因素对于及时干预和改善患者预后至关重要.
布拉登评分是评估压力风险的广泛使用的工具,但它在预测MODS死亡率方面的有用性不太清楚.

研究的目的:

调查最初的布拉登评分和被诊断为MODS的患者在ICU中的死亡率之间的关系.
确定布拉登分数是否可以作为MODS重症患者死亡率的预测标记.

主要方法:

从MIMIC-III和MIMIC-IV数据库中对37,981名MODS患者进行了回顾性分析.
使用多变量后勤回归模型来评估入院布拉登分数和所有原因的ICU死亡率之间的关联.
在多变量分析中对潜在的混因素进行控制.

主要成果:

在MODS患者的整体ICU死亡率为8.6%.
在最初的布拉登评分和ICU死亡率之间观察到显著的负相关性.
这种负相关性在多变量调整后仍然存在 (调整后OR=0.87,95% CI 0.85-0.88,P < 0.0001),表明较高的布拉登分数与较低的死亡率有关.

结论:

布拉登评分显示,在MODS患者中,与ICU内死亡率有显著的负相关性.
最初的布拉登评分可能成为MODS患者死亡风险的有价值的预测工具.
进一步的研究可以探索将布拉登评分纳入MODS管理的临床决策.

关键词:

布雷登得分布雷登得分在ICU的护士.机器学习机器学习死亡率死亡率死亡率多个器官衰竭多个器官衰竭.

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