探索津巴布韦年轻人和老年人之间艾滋病毒污名和治疗中断的差异
Venessa Chen1, Gnilane Turpin2, Omar Syarif3
1Johns Hopkins Bloomberg School of Public Health, Baltimore, United States. vchen28@jh.edu.
BMC public health
|November 22, 2025
概括
与老年人相比,艾滋病毒感染的年轻人经历了更高的抗逆转录病毒疗法 (ART) 中断率和耻辱感. 解决污名化的干预措施对于改善年轻人对ART的坚持至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会科学 社会科学 社会科学
背景情况:
- 艾滋病毒污名显著影响成年人抗逆转录病毒治疗 (ART) 的坚持.
- 在年轻成年人 (18-24岁) 中,人们对这种关系的理解较少.
- 在津巴布韦,研究了年轻人与与艾滋病毒感染的老年人之间的耻辱表现和ART中断.
研究的目的:
- 调查津巴布韦艾滋病毒感染者 (PLHIV) 的年轻人和老年人之间的耻辱和ART中断之间的联系.
- 为了比较青少年和老年PLHIV之间的耻辱和ART中断的流行率.
- 为了确定与ART中断相关的特定类型的耻辱.
主要方法:
- 来自2021年津巴布韦PLHIV污名指数2.0的横截面数据.
- ART中断被定义为永远停止或中断艾滋病毒治疗.
- 内化,预期和实施的耻辱被分类;修改Poisson回归用于分析,按年龄分层.
主要成果:
- 年轻成年人 (20.9%) 报告ART中断率高于老年人 (10.3%).
- 年轻人经历了更大的内化 (56.3%对41.7%) 和预期的耻辱 (73.9%对51.8%).
- 更高水平的内化,预期和实施的耻辱与ART中断的增加显著相关.
结论:
- 津巴布韦艾滋病毒感染的年轻人面临更高的ART中断率和耻辱感.
- 在这个人群中,耻辱是与ART中断相关的重要因素.
- 针对年轻人减少耻辱的干预措施对于优化ART坚持是必不可少的.
相关概念视频
Sexually Transmitted Infections
880
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
880
Retrovirus Life Cycles
49.2K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
49.2K
Pulmonary Tuberculosis I
811
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
811
Stereotypes, Prejudice, and Discrimination
94.8K
Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
94.8K
Ethics in Research
25.4K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.4K
Factors Affecting the Risk of Infection
13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K


