1型糖尿病儿童的白内障:来自北印度的一个单一中心的经验,涉及到一个未被认可的并发症
Devi Dayal1, Soumya Jyoti Raha2, Sayan Banerjee1
1Department of Pediatrics, Pediatric Endocrinology and Diabetes Unit, 29751 Post Graduate Institute of Medical Education and Research , Chandigarh, India.
Journal of pediatric endocrinology & metabolism : JPEM
|November 23, 2025
概括
白内障影响了1%以上的1型糖尿病 (T1D) 的儿童,通常出现在早期. 在诊断时及在第一年内进行早期查对于管理这种并发症至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 儿科内分泌学 儿科内分泌学
- 糖尿病学 糖尿病学
背景情况:
- 建议对患有1型糖尿病 (T1D) 的儿童进行白内障查.
- 有限的数据存在于白内障的流行率和相关因素在资源有限的设置.
研究的目的:
- 评估T1D儿童白内障的患病率.
- 在这个人群中确定与白内障发展相关的因素.
主要方法:
- 在北印度进行了回顾性,基于医院的观察性研究.
- 对患有白内障的T1D儿童 (2015-2025) 的临床,人体测量,生化和眼科数据的分析.
主要成果:
- 在1776名T1D儿童中,1.18%患有白内障.
- 14.2%的人在糖尿病诊断时患有白内障; 28.6%的人患有早期白内障.
- 毛里亚克综合征存在于38.1%的病例中;HbA1c和白内障发病间隔之间的负相关性 (r=-0.468,p=0.032).
结论:
- T1D儿童的白内障可能在早期出现,可能与代谢控制或自身免疫因素有关.
- 建议在诊断时和第一年内进行查.
- 对于早期检测和管理,需要特定区域的指南.
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