在被食少铜饮食的狗中,肝脏铜积累的风险较低,而不是那些被食充满铜饮食的狗
Sharon A Center1, Philip VanVranken2, John F Randolph1
11Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.
Journal of the American Veterinary Medical Association
|November 23, 2025
概括
高龄犬可以安全地食用限制铜 (Cu) 的饮食,摄入高达0.24毫克Cu/100千卡的摄入量被很好地容忍. 饮食中较高的铜含量在本研究人群中没有表现出不良影响.
科学领域:
- 兽医营养学 兽医营养学
- 狗的健康 狗的健康
- 毒理学 毒理学 毒理学
背景情况:
- 食中的铜 (Cu) 是狗的必需微量营养素,但过量摄入可能会导致毒性.
- 确定可容忍的上限摄入水平对于制定安全有效的老犬饮食至关重要.
- 之前的研究还没有明确确定初级保健机构中老年犬的安全食Cu水平.
研究的目的:
- 估计老年狗的可容忍饮食中的铜 (Cu) 摄入量.
- 为了评估饮食中的Cu摄入量与老年犬肝脏Cu度之间的关系.
- 为了确定老年狗中铜积累的潜在风险因素.
主要方法:
- 从104只老犬的肝脏样本中分析了Cu度和组织学变化.
- 饮食中的Cu摄入量根据kcal.cal被分为Cu-限制或Cu-补充.
- 医疗记录,饮食史和水分分析与肝脏Cu水平相关.
主要成果:
- 那些受限饮食 (0.15-0.24 mg Cu/100 kcal) 的狗没有出现Cu缺乏症的迹象.
- 与Cu补充饮食相比,受Cu限制饮食的狗的肝脏Cu度明显较低.
- 在受研究的人群中,水并未被确定为Cu的重要来源.
结论:
- 对于老年犬来说,可容忍的0.24 mg Cu/100 kcal的食上限摄入量是指定的.
- 饮食中的Cu水平显著影响老犬的肝脏Cu度.
- 目前对老年犬的饮食建议可能需要调整,以防止潜在的Cu过载.
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