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在糖尿病病中,ANXA1通过解蛋白1改善线粒体平衡

Zi-Han Li1, Lu Fang2, Liang Wu1

  • 1Renal Division, Department of Medicine, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, China; Department of Nephrology, Peking University First Hospital, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China; Research Units of Diagnosis and Treatment of Immune-mediated Kidney Diseases, Chinese Academy of Medical Sciences, China.

Journal of advanced research
|November 23, 2025
PubMed
概括

附件A1 (ANXA1) 通过稳定GATA3来增加UCP1.1,从而减轻糖尿病病 (DN). 这增强了心血管蛋白合成,减少了线粒体分裂,并治疗DN,突出了UCP1作为治疗点.

关键词:
附录A1 附录 A1 是一个附录.卡迪奥利平合成酶 1 的作用.糖尿病脏病 糖尿病脏病GATA 结合蛋白 3 的结合蛋白.线粒体动力学的动态解蛋白1 解蛋白1 是一个解蛋白.

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