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Updated: Jan 10, 2026

Production of Monoclonal Antibodies Targeting Aminopeptidase N in the Porcine Intestinal Mucosal Epithelium
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纳米组件用于口服蛋白质输送 - - 单克隆组件用于炎症性肠病的案例

Ana M López-Estévez1, María G Portela1, Laura Piñeiro-Alonso1

  • 1Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain; Health Research Institute of Santiago de Compostela, 15782 Santiago de Compostela, Spain; Department of Pharmacology, Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.

Journal of controlled release : official journal of the Controlled Release Society
|November 23, 2025
PubMed
概括

这项研究引入了一种新的纳米载体系统,用于口服输送治疗性蛋白质,如单克隆抗体 (mAbs). 开发的纳米组件 (NA) 通过增强结肠中药物保留来治疗炎症性肠病 (IBD) 的潜力.

关键词:
生物分布 生物分布炎症性肠病是一种炎症性肠病.胰岛素是一种胰岛素.单克隆抗体是一种单克隆抗体.纳米颗粒 纳米颗粒口服/蛋白质输送方式有关PET/MRI的研究.

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