评估患者和家庭报告的结果指标和多发性骨髓瘤临床参数之间的相关性
Mouna Ballan-Haj1, Kareem Midlej2,1, Barbara Silverman2
1Institute of hematology, Lady Davis Carmel Medical Center, 7 Michal St, Haifa, Israel.
Scientific reports
|November 23, 2025
概括
患者报告结果指标 (PROM) 和家庭报告结果指标 (FROM) 显示了多发性骨髓瘤患者和护理人员的改善. 这些措施与更好的疾病状况和生活质量相关.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 护理人员支持护理人员支持
背景情况:
- 多发性骨髓瘤 (MM) 呈现复杂的症状,并对患者和护理人员产生重大影响.
- 传统的评估工具可能无法完全捕捉患者和护理人员的经验.
研究的目的:
- 在活跃的MM患者中评估患者报告的结果指标 (PROM) 和家庭报告的结果指标 (FROM).
- 探索PROMs/FROM-16和标准疾病评估参数之间的关联.
- 评估患者报告结果和护理人员负担随着时间的推移而发生的变化.
主要方法:
- 这是一项为期12个月的前性观察性研究,涉及活跃的MM患者.
- 每季度管理PROM和FROM-16问卷.
- 斯皮尔曼相关性,弗里德曼和威尔科克森的数据分析测试.
主要成果:
- 改善的疾病评估与更好的患者报告的症状/副作用以及减少护理人员负担相关 (FROM-16).
- 有利的CRAB标准 (,脏,贫血,骨病变) 与较高的PROM和较少的护理者影响有关.
- 患者PROM反映了护理人员的挑战;生活质量,症状,身体形象和未来前景领域显示出临床上显著的改善.
结论:
- 从他们的角度来看,PROM/FROM-16对于评估MM患者状态和护理人员负担是有价值的.
- 这些措施可以为量身定制的治疗方法提供信息,并突出显示护理人员支持的需要.
- 进一步研究MM的护理人员经验是必不可少的.
相关概念视频
01:21Cancer Survival Analysis
633
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
633
01:11Guidelines for Writing Outcome
3.6K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
3.6K
01:24Kaplan-Meier Approach
541
The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
541
01:20Comparing the Survival Analysis of Two or More Groups
541
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
541