种族是否会影响经过修复性直肠切除术与阴道囊解剖术后的长期结果?
Olga Lavryk1, Arielle Kanters1, Hermann Kessler1
1Department of Colorectal Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
概括
种族/族裔影响了阴道囊解 (IPAA) 后的结果. 白人患者的囊炎发病率较高,而非白人的患者报告了更多的社会限制,尽管长期的囊存活率相似.
科学领域:
- 胃肠病学和外科手术
- 炎症性肠道疾病研究研究
- 手术结果分析手术结果分析
背景情况:
- 众所周知,种族和民族差异会影响炎症性肠病 (IBD) 的表现和治疗.
- 种族和族裔对囊门解症 (IPAA) 结果的具体影响仍然在很大程度上未被描述.
- 这项研究旨在调查种族/种族对IPAA结果的影响.
研究的目的:
- 为了确定种族/族裔是否会影响阴道囊解 (IPAA) 的结果.
- 为了比较白人和非白人IPAA患者之间的并发症率,囊存活率,功能结果,生活质量和生活方式限制.
主要方法:
- 分析了1983年至2022年间接受IPAA治疗的4954名患者的大队.
- 根据现有的种族/种族数据,患者被分为白人和非白人.
- 评估的结果包括人口统计学,术后并发症 (泄漏,败血症,狭窄,囊炎,,阻塞),囊存活率,功能指标 (便频率,透率),生活质量 (QoL) 评分以及社会,饮食和性限制.
主要成果:
- 虽然白人和非白人患者的整体囊存活率相似 (15年后为95-97%),但在并发症方面观察到显著差异.
- 与非白人患者相比,白人患者的囊炎 (29%与18%相比),抽 (8%与4.5%相比) 和术后阻塞 (13%与9%) 的发生率更高.
- 非白人患者报告了显著更多的社会限制 (25%对15%),尽管生活质量得分相似.
结论:
- 种族/种族与IPAA后的差异性并发症概况有关,白人患者经历了更多的囊炎,非白人患者面临更大的社会限制.
- 长期保持袋子和生活质量似乎在种族/族群之间是可比的.
- 需要进一步的研究来阐明IPAA结果中这些与种族/种族相关的差异背后的机制.
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