支气管肺发育不良的定义作为预测儿童早期的肺功能
Brianna C Aoyama1, Sharon A McGrath-Morrow2, Joseph M Collaco1
1Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Pediatric pulmonology
|November 24, 2025
概括
较新的支气管肺功能障碍 (BPD) 定义更好地预测早产婴儿的肺功能受损. 然而,目前的BPD分类需要改进,以改善长期呼吸结果的预测.
科学领域:
- 儿科肺病学 儿科肺病学
- 新生儿科学 新生儿科学
- 临床流行病学临床流行病学
背景情况:
- 支气管肺功能障碍症 (BPD) 是一种慢性肺部疾病,会影响早产婴儿.
- 准确的BPD定义对于预测长期呼吸道结果至关重要.
- 现有的定义在临床实用性和预测能力上有所不同.
研究的目的:
- 评估三种BPD定义 (2001 NHLBI, 2018 NICHD, 2019 NRN) 的临床实用性和预测能力.
- 评估它们在预测早产和BPD病史儿童的肺功能方面的有效性.
主要方法:
- 对138名患有早产和BPD史的儿童进行了回顾性图表审查.
- 肺部疾病的分类使用三个BPD定义.
- 回归分析以将肺功能 (FEV1,FVC) 与BPD状态和严重程度相关联.
主要成果:
- 没有一个定义完美地确定了风险和分层严重程度.
- 2018年NICHD和2019年NRN定义确定了与对照组相比,BPD患者的下肺功能.
- 2001年的NHLBI定义显示了随着严重程度的增加而恶化的肺功能梯度.
结论:
- 较新的BPD定义 (2018年NICHD,2019年NRN) 在识别患有肺功能障碍风险的儿童方面优于2001年NHLBI定义.
- 补充氧气需求和肺高血压史可能是长期呼吸道结果的更强有力的预测因素.
- 完善BPD定义是必要的,以提高预测价值和指导管理.
更多相关视频
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
51.9K
06:11Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
Published on: February 9, 2022
6.2K
相关概念视频
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.5K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.5K
01:17Pulmonary Cycle: Exhalation
3.0K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
3.0K
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
3.1K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
3.1K
01:25Pulmonary Function Tests
720
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
720
01:22Chronic Obstructive Pulmonary Disease
2.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.2K
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
3.5K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.5K