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多组学和分子动力学分析用于慢性鼻炎与鼻的生物标志物发现

Qian Guo1, Xinjie Qiao1, Shuman Huang1

  • 1Department of Rhinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Chemical biology & drug design
|November 24, 2025
PubMed
概括

金色葡萄球菌的α毒素通过NF-κB/TGF-β通路促进了长期鼻多性鼻炎 (CRSwNP) 中的表皮质-介质细胞过渡. PRKCZ被确定为CRSwNP治疗的潜在治疗标.

关键词:
在CRSwNP中使用.在 NF-κBB 中.分子对接的分子对接.进行多主题分析.一个单细胞分析分析.治疗目标是治疗的目标.

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