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法国嗅觉障碍问卷-10的有效性和可靠性
Jérôme R Lechien1,2,3,4,5, Luigi A Vaira5,6,7, Lea Lamoulen8
1Department of Surgery, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.
概括
一个新的短法语嗅觉障碍问卷 (Fr-ODQ-10) 已被验证用于嗅觉功能障碍患者. 这份10项问卷是可靠的,并且与嗅觉测试结果有显著的相关性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 心理物理学的精神物理.
背景情况:
- 法国嗅觉问卷可能很长,可能会影响患者的参与.
- 嗅觉功能障碍 (OD) 的诊断和管理需要有效的评估工具.
研究的目的:
- 开发和验证一个简洁的法语版本的嗅觉障碍问卷 (Fr-ODQ-10).
- 评估Fr-ODQ-10用于评估嗅觉功能的可靠性和有效性.
主要方法:
- 一项前性多中心研究,涉及OD患者和无症状对照.
- 统计分析从完整的 Fr-ODQ 中确定了 Fr-ODQ-10 的 10 个关键项目.
- 评估了内部一致性 (克朗巴赫α),测试重试可靠性和外部有效性 (与TDI和Fr-ODQ的相关性).
主要成果:
- Fr-ODQ-10显示出高的外部有效性,与TDI测试 (rs=0.228,P=.001) 和全Fr-ODQ (rs=0.875,P=.001) 有显著的相关性.
- 内部有效性很高,与OD患者相比,对照组的得分明显较低 (P=.001).
- 观察到良好的内部一致性 (α=0.796) 和适当的外部一致性. 在治疗后,Fr-ODQ-10下降,得分超过7.5表示异常 (灵敏度:84.8%,特异性:84.2%).
结论:
- Fr-ODQ-10是评估嗅觉障碍的有效和可靠的临床工具.
- 它的简洁性增强了患者的参与,使其成为临床使用的实用工具.
- Fr-ODQ-10与心理物理嗅觉评估有很好的相关性,有助于诊断和治疗监测.
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