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Updated: Jan 10, 2026

Development of an In Vitro Assay to Evaluate Contractile Function of Mesenchymal Cells that Underwent Epithelial-Mesenchymal Transition
06:02

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Published on: June 10, 2016

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TNF-α通过组织蛋白甲基转移酶Setdb2抑制纤维细胞向肌纤维细胞的转变

Tyler M Bauer1, Kevin D Mangum1, Samuel D Buckley1

  • 1Department of Surgery.

JCI insight
|November 24, 2025
PubMed
概括

在糖尿病性伤口中,蛋白质SETDB2损害了纤维细胞向肌纤维细胞的过渡. 针对TNF-α/STAT3/SETDB2通路可以通过恢复这一关键修复过程来增强伤口愈合.

关键词:
皮肤病学 皮肤病学糖尿病 糖尿病 糖尿病表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.免疫学 免疫学 免疫学

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