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Updated: Jan 10, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
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Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

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对双重活性肝脏和血液阶段抗等离子体药物的机制性见解

Mukul Rawat1,2, Nonlawat Boonyalai1, Cindy Smidt2

  • 1Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, United Kingdom.

mBio
|November 24, 2025
PubMed
概括

研究人员通过进化寄生虫对化合物的耐药性来确定新的抗疟疾药物点. 四个验证的标包括乙CoA合成酶和蛋白激酶G,为新的疟疾治疗提供了潜力.

关键词:
抗疟疾药物的使用.药物耐药性机制 抗药性机制疟疾 疟疾 是一种疾病.

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