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Updated: Jan 10, 2026

A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl
05:20

A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl

Published on: November 28, 2014

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产生大酶B的B细胞:与乳腺癌细胞的双向关系以及对免疫治疗的含义

Hosein Hakimi1, Fereshteh Mehdipour2, Morteza Samadi3

  • 1Department of Immunology, School of Medicine, Shahid Sadoughi University of Medical Sciences Yazd, Iran.

American journal of clinical and experimental immunology
|November 24, 2025
PubMed
概括

乳腺癌细胞通过直接接触来抑制产生Granzyme B (GrB) 的B细胞. 然而,用IL-21和抗BCR激活B细胞可以逆转这种抑制,并恢复对瘤细胞的细胞毒性潜力.

关键词:
B 细胞 B 细胞 B 细胞大酶B 种子乳腺癌 乳腺癌 乳腺癌瘤排水淋巴结的淋巴结.

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