在2型糖尿病中,心肺健康与血管功能受损之间的关联是2型糖尿病
Shi-Ting Zhao1,2, Yi-Ming Zhu3, Ying-Ying Chen4
1Department of General Practice, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing 210009, Jiangsu Province, China.
World journal of diabetes
|November 24, 2025
概括
更高的心肺呼吸能力 (CRF) 与2型糖尿病患者更好的血管功能有关. 改善的CRF降低了血管健康受损的可能性,这是心血管疾病风险的关键因素.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 运动生理学 运动生理学
背景情况:
- 心血管健康 (CRF) 与心血管疾病风险相反相关.
- 血管功能对于心血管健康至关重要.
- 在2型糖尿病中,CRF与血管功能之间的联系尚不清楚.
研究的目的:
- 研究2型糖尿病患者心肺呼吸能力和血管功能之间的关联.
- 为了确定更高的CRF水平是否与改善的血管健康标志物相关.
主要方法:
- 包括343名2型糖尿病患者 (年龄≥18岁) 接受了运动测试.
- 使用血管健康指数 (VHI) 评估血管功能,这是一个复合得分.
- VHI的组成部分包括脚-手臂指数,截面氧气压,脉冲波速度和动脉内膜-介质厚度.
主要成果:
- CRF与VHI正相关 (β = 0.10,P = 0.047),特别是在脚-手臂指数和脉冲波速度方面.
- 更高的CRF类别与血管功能受损的几率明显降低 (OR = 0.44).
- 在CRF中的每一个代谢等效增加都降低了血管功能受损的几率 (OR = 0.73).
结论:
- 提高心肺呼吸能力与2型糖尿病中血管功能增强有关.
- 在这个患者群体中,较高的CRF水平与血管功能受损的风险降低相关.
- 这些发现凸显了CRF在2型糖尿病管理中的血管健康的重要性.
相关概念视频
Carbohydrate Metabolism
13.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
13.7K
Diabetes Mellitus: Type 2 and Gestational
4.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.3K
Coronary Artery Disease I: Introduction
857
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
857
Diabetes Mellitus: Overview and Type I Subtype
4.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.8K
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K
Diabetes: Symptoms, Diagnosis, and Complications
2.0K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.0K


