在不平坦地形行走期间,电皮质动态的年龄差异
Chang Liu1,2, Erika M Pliner1,3, Jacob Salminen1
1Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA.
bioRxiv : the preprint server for biology
|November 24, 2025
概括
与年轻人相比,老年人在不平坦的地形上表现出增加的步态变化和减少的大脑活动调制. 这表明皮层灵活性下降可能会影响衰老中的移动性.
科学领域:
- 神经科学是一个神经科学.
- 生物力学 生物力学
- 老年学是一门学科.
背景情况:
- 随着年龄的增长,步态控制变得不那么自动,这影响了在具有挑战性的表面上的移动性.
- 使用高密度脑电图 (EEG) 的移动脑成像可以了解与年龄相关的移动性下降的神经机制.
研究的目的:
- 在不平坦地形行走时,量化与年龄相关的大脑活动 (电皮质动力学) 的差异.
- 为了比较年轻人和老年人之间的平均和步骤内脑活动变化.
主要方法:
- 31名年轻人和71名老年人走在不同难度的不平坦地形跑步机上.
- 高密度脑电图 (EEG) 记录了大脑活动,分析了α和β频段的功率光谱变化.
- 测量了步行参数,如步骤持续时间和十字路口外行的变化.
主要成果:
- 老年人显示,随着地形不均,步态变化 (步数持续时间,十字路口游览) 的增加更大.
- 这两个年龄组在不平坦的地形上表现出广泛的脑活动变化,特别是在α和β波段.
- 较年轻的成年人与不平坦的地形相比,尾角α/β功率的减少更大;较年长的成年人在不平坦的地形上显示出较少的调制和增加的尾活动波动.
结论:
- 年长的成年人表现出增加的步态变化,但皮质网络的灵活性降低,由缺乏与任务相关的大脑活动调节所表明.
- 老年人脑脊活动调节的减少表明,即使在稳定的表面上,视觉处理也可能过度依赖视觉处理,从而限制了对不平坦地形的适应能力.
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