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Updated: Jan 10, 2026

Detection of Protein Ubiquitination
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通过促进乌比基参与,Faf1加速了p97介导的蛋白质展开

Zengwei Liao1,2,3, Connor Arkinson1,2,3, Andreas Martin1,2,3,4

  • 1California Institute for Quantitative Biosciences, University of California at Berkeley, Berkeley, CA 94720, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

蛋白质展开酶p97/VCP,与辅因子Faf1,通过增强初始的泛素展开和运动参与,加速泛素链处理. Faf1稳定了Ufd1-Npl4辅因子,揭示了p97基质选择的复杂调节.

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