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Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes
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来自1型糖尿病患者的亲炎性循环细胞外囊泡有助于贝塔细胞细胞毒性和疾病致病性

Nagesha Guthalu Kondegowda, Zelda Cisneros, Daniel Roeth

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    来自1型糖尿病 (T1D) 患者的循环细胞外囊泡 (cEVs) 诱导β细胞死亡,导致疾病的发展. 这些发现表明,CEVs可能作为T1D的早期生物标志物和治疗点.

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