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Updated: Jan 10, 2026

Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors
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一种基于诱导多能干细胞的化学遗传方法,用于研究脊髓肌肉缩

Richard M Giadone1,2,3, Kristina M Holton1,2,3,4, Xiaoyu Hu1,2

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

研究人员调整了一个化学遗传平台来研究脊柱肌肉缩 (SMA). 这种方法分析了SMA患者衍生的神经元中的基因表达,有助于发现神经系统疾病的药物.

关键词:
连接地图 (CMAP) 是一个连接地图.L10001000 的时间.脊椎肌肉缩 (SMA) 是一种疾病.化学遗传查 化学遗传查这些是iPSCs.

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