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Updated: Jan 10, 2026

Generation of Standardized and Reproducible Forebrain-type Cerebral Organoids from Human Induced Pluripotent Stem Cells
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Generation of Standardized and Reproducible Forebrain-type Cerebral Organoids from Human Induced Pluripotent Stem Cells

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区域间的人类组合物回顾胎儿大脑形态,并增强神经元复杂性.

André Saraiva Leão Marcelo Antunes1,2, Maria Carolina Pedro Athié1,2, Ana Clara Caznok Silveira3

  • 1Brazilian Bioscience National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas, 13083-100, Brazil.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

人类神经器官和组合体模拟胎儿大脑神经元,组合体显示出更大的复杂性. 这项研究描述了这些模型中的神经元形态,用于大脑发育和疾病研究.

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Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains

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相关概念视频

Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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