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Updated: Jan 10, 2026

Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin
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Published on: September 12, 2019

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药理上激活HNF4α/γ 恢复皮质屏障功能在克罗恩氏病

Debasish Halder, Amin Ghazi, Yaohong Wang

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    肝细胞核因子HNF4α/γ调节克罗恩病 (CD) 中的肠道屏障完整性. 这些因素的丧失会损害屏障功能,但植物衍生激动剂 (NCT和NFT) 可以恢复它,为CD提供潜在的治疗方法.

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