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Updated: Jan 10, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

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Hi-C知情核关联测试:将3维基因组结构集成到变异组关联中,以获得全基因组测序数据

Yueyang Huang1, Riddhik Basu2, Wenbin Lu2

  • 1Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA.

bioRxiv : the preprint server for biology
|November 24, 2025
PubMed
概括

这项研究引入了一种全新的Hi-C知情内核关联测试,用于全基因组序列数据. 这种方法通过将3D基因组架构整合到遗传关联测试中来增强罕见变异组的检测.

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