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Updated: Jan 10, 2026

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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致病性通过阻断eIF4B介导的局部蛋白质合成来抑制突触可塑性

Grant Kauwe, Doyle Lokitiyakul, Ivy L Wong

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    阿尔茨海默氏症中的致病性陶通过阻断神经元中的蛋白质合成来破坏记忆. 针对tau-eIF4B相互作用,可以恢复突触可塑性和记忆形成.

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