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Updated: Jan 10, 2026

Heteromulticellular Stromal Cells in Scaffold-free 3D Cultures of Epithelial Cancer Cells to Drive Invasion
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瘤细胞扩散是通过调节性T细胞驱动的细胞外矩阵重塑来促进的

Ailen D Garcia-Santillan, Jessanne Y Lichtenberg, He Shen

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    调节性T (Treg) 细胞改变瘤细胞外基质 (ECM),促进乳腺癌细胞迁移和转移. 这种由Treg细胞驱动的ECM重塑与较差的患者存活率相关,并涉及与瘤相关的巨细胞.

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