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Updated: Jul 27, 2026

Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction
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Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

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对于产后心脏发育和心脏功能,需要Whsc2/NelfA-依赖的转录复合体

Saleena Alikunju, Chandni Thakkar, Aishwarya Venkatasubramanian

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    负延长因子A (NELFA) 对产后心脏发育至关重要. 心肌细胞中NELFA的损失导致大心肌病和小鼠的早期死亡,突出其在心脏基因表达中的作用.

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