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Updated: Jan 10, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

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单细胞全基因组和转录组测序将人体突变与细胞身份和祖先联系起来

Abhiram Natu, Mrunal K Dehankar, Reenal Pattni

    bioRxiv : the preprint server for biology
    |November 24, 2025
    PubMed
    概括

    单细胞全基因组放大 (scWGA) 能够对体位突变进行全面的分析. 这种强大的技术揭示了细胞类型特定的突变模式,并有助于重建细胞系,用于人类发育和疾病研究.

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